Recombinant Human INF-alpha 16 Protein
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The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties.
| SKU | OPTIONS | 价格 | |
|---|---|---|---|
| INFA16-100 | 50 ug (1 mg/ml) | Please inquire | |
| INFA16-200 | 1 mg (1 mg/ml) | Please inquire | |
| INFA16-300 | 100 mg (10 mg/ml) | Please inquire | |
| INFA16-400 | 1 g (10 mg/ml) | Please inquire | |
| INFA16-OEM | Any size | Please inquire |
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描述
Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α16 (interferon α 16) belongs to type 1 interferon family. IFN-α16 is induced in peripheral blood mononuclear cells (PBMCs) upon incubation with CpG-oligonucleotides and in plasmacytoid dendritic cells upon incubation with CpG-oligonucleotides or imiquimod. Human IFN-α16 is classified as an intermediate ISG inducer with a moderate capacity to induce IFIT1, CXCL10, CXCL11, ISG15 and CCL8.
Human IFN-α16 expression is IFN-α receptor-dependent (i.e. induced by other IFN-α subtypes) only under conditions of low viral multiplicity of infection (MOI) of Sendai virus in vitro.
Full Name
Interferon α 16
Source
E. coli
Species
Human
Accession #
P05015
Molecule Weight
The mature recombinant human IFN-α16 is a 22 kDa protein (24-189aa).
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
其他信息
| OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
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