Recombinant Human Amphiregulin (AR) Protein
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Amphiregulin (AR) is an EGF related growth factor that signals through the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts.
| SKU | OPTIONS | 价格 | |
|---|---|---|---|
| AR-100 | 50 ug (1 mg/ml) | Please inquire | |
| AR-200 | 1 mg (1 mg/ml) | Please inquire | |
| AR-300 | 100 mg (10 mg/ml) | Please inquire | |
| AR-400 | 1 g (10 mg/ml) | Please inquire | |
| AR-OEM | Any size | Please inquire |
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描述
Description
Amphiregulin (AR) is an EGF related growth factor that signals through the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity.
Full Name
Amphiregulin
Source
E. coli
Species
Human
Accession #
Q5U026
Molecule Weight
The mature recombinant human AR is a 11 kDa protein containing 98aa (S101-K198).
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Activity
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 5-15 ng/mL.
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
其他信息
| OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
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