Recombinant Human INF-alpha 1 Protein
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The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties.
| SKU | OPTIONS | 价格 | |
|---|---|---|---|
| INFA1-100 | 50 ug (1 mg/ml) | Please inquire | |
| INFA1-200 | 1 mg (1 mg/ml) | Please inquire | |
| INFA1-300 | 100 mg (10 mg/ml) | Please inquire | |
| INFA1-400 | 1 g (10 mg/ml) | Please inquire | |
| INFA1-OEM | Any size | Please inquire |
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描述
Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α1 (interferon α 1) belongs to type 1 interferon family, and is a lymphoid factor. IFN-α1 interacts with IFNAR1 (interferon α receptor 1) and IFNAR2. The interaction activates JAK1 (janus-activated kinase 1) and tyrosine kinase 2. These events phosphorylate and activate STAT1 and STAT2 (signal transducer and activator of transcription proteins), leading to the upregulation of interferon-stimulated genes some of which encode antiviral proteins.
Full Name
Interferon α 1
Source
E. coli
Species
Human
Accession #
J00210
Molecule Weight
The mature recombinant human IFN-α1 is a 19.3kDa protein containing 166 amino acid residues.
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
其他信息
| OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
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