Recombinant Human INF-alpha 2 Protein
¥0.00
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties.
| SKU | OPTIONS | 价格 | |
|---|---|---|---|
| INFA2-100 | 50 ug (1 mg/ml) | Please inquire | |
| INFA2-200 | 1 mg (1 mg/ml) | Please inquire | |
| INFA2-300 | 100 mg (10 mg/ml) | Please inquire | |
| INFA2-400 | 1 g (10 mg/ml) | Please inquire | |
| INFA2-OEM | Any size | Please inquire |
- 描述
- 其他信息
- Documents
- Q&A
描述
Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α2 (interferon α 2) belongs to type 1 interferon family. IFN-α2 augments the suppressed immune functions in patients with head and neck squamous cell carcinoma (HNSCC). IFN-α2 initiated T and NK cell mediated cytotoxicity of tumor cells through IFNγ dependent and independent mechanisms. IFN-α2 enhances suppressed T cell cytotoxicity by stimulation of the perforin-granzyme B system (IFNγ dependent).
Full Name
Interferon α 2
Source
E. coli
Species
Human
Accession #
NM_000605
Molecule Weight
The mature recombinant human IFN-α2 is a 19.4 kDa protein containing 166 amino acid residues.
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Activity
Specific activity is 1.86 x 108 units/mg, as determined in a cytopathic effect inhibition assay using EMC virus on A549 cells.
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
其他信息
| OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
|---|
There is no documents for this product.Will be available soon.
The Q&A for this product will be available soon.