Recombinant Human INF-kappa Protein
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The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties.
| SKU | OPTIONS | 价格 | |
|---|---|---|---|
| INFK-100 | 50 ug (1 mg/ml) | Please inquire | |
| INFK-200 | 1 mg (1 mg/ml) | Please inquire | |
| INFK-300 | 100 mg (10 mg/ml) | Please inquire | |
| INFK-400 | 1 g (10 mg/ml) | Please inquire | |
| INFK-OEM | Any size | Please inquire |
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描述
Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN- κ (interferon kappa) is a 24 kDa secreted, nonglycosylated polypeptide that belongs to the IFN-κ subclass of the type I interferon family of cytokines. It is expressed by macrophages in mice, and monocytes, dendritic cells and keratinocytes in human. IFN-κ induces TNF-α, IL-10 and MCP-1 production by monocytes.
Full Name
Interferon kappa
Source
E. coli
Species
Human
Accession #
Q9P0W0
Molecule Weight
The mature recombinant human IFN-κ is a 21 kDa protein (22-199aa).
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Activity
Measured in an anti-viral assay using L‑929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.2-1.2 ng/mL.
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
其他信息
| OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
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