Cas13d

¥0.00¥11,434.00

Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR-associated (Cas) proteins to cleave foreign genetic material. Cas13d is part of the Type VI CRISPR-Cas system.

SKU: SKU496752 Categories: , , ,
SKU OPTIONS 价格
CAS13d-100 Cas13d (100 μg,1 mg/ml) ¥2,298.00
CAS13d-200 Cas13d (1 mg,1 mg/ml) ¥11,434.00
CAS13d-300 Cas13d (100 mg,10 mg/ml) Please inquire

Description

Description
Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material.

CasRx, Cas13d from Ruminococcus flavefaciens
XPD3002, was highly active and short, 112KD.

In addition to programmable RNase activity, all Cas13d exhibit collateral activity after recognition and cleavage of a target transcript, leading to non-specific degradation of any nearby transcripts regardless of complementarity to the spacer.

Applications
• Targeted RNA knockdown
• RNA editing
• Nucleic acid detection

Source
E. coli

Organism
Ruminococcus flavefaciens XPD3002 (CasRx),

Molecule Weight: 112KD

Purity
> 95 % as determined by SDS-PAGE

Storage
-20 °C. Avoid repeated freeze-thaw cycles.

Cas13 Storage Buffer (Click to Order)
0.3 M NaCl
20 mM Tris-HCl, pH 8.0
0.5 mM EDTA
1 mM DTT
50% Glycerol

10X Cas13 Reaction Buffer (Click to Order)
200 mM HEPES, 50 mM MgCl2, 1 M NaCl, 1 mM EDTA, pH 6.5

10X Cas13 sherlock reaction buffer (requested)
200 mM HEPES, 90 mM MgCl2, pH 6.8

Additional information

OPTIONS

Cas13d (100 μg,1 mg/ml), Cas13d (1 mg,1 mg/ml), Cas13d (100 mg,10 mg/ml), Cas13 Buffer (10X Cas13 Reaction Buffer,200 ul), Cas13 Buffer (10X Cas13 Reaction Buffer,1 ml)

COA ( Certificate of Analysis )

MSDS & Certificates